A 27-year-old woman walks in looking totally normal…
Except for one tiny detail:

✅ Angry red rash
✅ All over her torso
✅ And somehow…
✅ Smells exactly like maple syrup?

Not fruity. Not sweaty-gym-socky.
Straight-up IHOP on a Sunday morning. 🥞🍁

Nurses were confused. Patients were hungry.
One doctor almost grabbed butter.

So what on earth was happening?

🧠 First thoughts in the ER

Doctors ran through the usual suspects:

• Fungal infection? No, that smells like musty chees
• Bacterial infection? No, that smells like rotting garbage
• Yeast infection? Close, but that gives bread factory vibes
• Maple syrup urine disease? Duh! Could be, but the patient is 27 and alive and well all her life so far...

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So… not a classic infection smell, not a metabolic disorder she should’ve been diagnosed with at birth…

What else smells sweet AND shows up on the skin?

🧪 Lab results drop

✔ No bacteria
✔ No fungus
✔ Normal metabolism
✔ But her sweat sample? Full of maple-scented compounds

Then the doctor asked one critical question:

And boom. Lightbulb. 💡

✅ Final Diagnosis: Contact Dermatitis from Artificial Flavoring Oils

She worked at a bakery — and had spent 8 hours handling a maple-syrup flavor concentrate without gloves.

Those oils are:

🔥 Highly concentrated
🚫 Not meant for direct skin contact
🌡️ Irritating to sensitive skin
🍁 And powerful enough to make a human smell like a pancake

It triggered:

• Allergic/irritant contact dermatitis (the rash)
• Fragrance compound absorption into the skin (the syrup smell)

Basically:
​She didn’t have a disease. She had a career hazard… and smelled delicious.

🥞 Treatment

✔ Removed exposure
✔ Topical steroid cream
✔ Antihistamines for itching
✔ A mandatory break from pancake production

Symptoms resolved in a few days.
Everyone in the ER is still craving brunch :)

🧬 Important note

This is not the same as Maple Syrup Urine Disease (MSUD), a rare genetic metabolic condition that:

• appears in infancy
• smells like syrup in urine, earwax, or sweat
• is due to amino acid metabolism deficiency
• can be life-threatening if untreated

Our maple-scented patient?
Just a victim of delicious occupational exposure.

🩺 Take-Home Lessons

🍁 Sweet-smelling rash isn’t always a metabolic disorder
🍁 Occupational exposures matter more than we think
🍁 Not all that smells like syrup should be served with pancakes
🍁 Gloves are an underrated fashion accessory in the workplace

💬 The bigger question…

If you smelled like food for 24 hours, would you choose:

A) Maple syrup
B) Vanilla
C) Garlic bread
D) Absolutely not, please let me smell human

Reply to this email with your answer 😆

For more medical content, and in particular, a video on how your job could be killing you (even literally!) do check out our Youtube channel

Be well,
👩‍⚕️ Dr. Joanna​
​AskADoc4Advice — where medicine meets curiosity (and a little bit of weird).

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